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Innovation & Development

What is Bioelectronic Medicine?

Bioelectronic medicines
are diagnostics and treatments that read and modulate electrical activity of the nervous system. Of all the bioelectronic medicines with treatment purpose, the commonly known medical devices are cardiac pacemakers for arrhythmias, vagus nerve stimulators for epilepsy, spinal cord stimulators for pain, and transcutaneous electrical nerve stimulators for rehabilitation. Although most bioelectronic medicine treatments use invasive approach, with the risks posed on patients, non-invasive approach is favored. Indeed, legally marketed non-invasive therapeutic applications of bioelectronic biomedicines have increased in neurological diseases, such as Parkinson’s Disease, Attention Deficit Hyperactivity Disorder, and even in brain cancers. So far, there has not been any bioelectronic medicines for other diseases treatment legally marketed yet.


TRWR focuses on non-invasive bioelectronic medicines research and development for chronic diseases treatment instead. TRWR applies transcutaneous electrical nerve stimulation to treat diabetes, pain and sleep disorder with pre-clinical and clinical validations following international regulatory requirements for treatment safety and efficacy.

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The concept of resonant waves originates from the ability of living organisms to sense the external electric fluctuations. Since the components of atoms (protons and electrons) are charged and oscillate all the time, the oscillating pattern is derived from the oscillation characteristics of its own atomic composition, thus any matter carries specific resonant frequency. If a wave with a specific intensity and resonant frequency can make some effect on a specific biological structure, this wave can be named “biological resonant wave”. For example, a string or a tuning fork itself has a specific resonant frequency. It will sense the same frequency sound wave from a distance and absorb the energy, producing vibration. This phenomenon is “resonance” and is also the basic mechanism of a biological resonant wave can regulate the physiological status of specific tissue or organ externally. A single organism, from cells, tissues, organs, to systems, has a unique resonance frequency (for example, the heart and lungs have different resonance frequencies) due to the different basic molecular content and structure. However, the same structure (like liver) among people shares similar frequency, since the composition and function do not vary from person to person, so everyone’s liver has a similar resonant frequency band.

In the past, the molecular mechanism of drugs has played an important role in mainstream medicine. Nowadays, non-invasive resonant wave technology has also become mature in medicine application. For example, non-invasive image detection has been quite advanced and popular. The principle is that when a resonant wave passes through the organism, there will be some unevenness in the resonance state and intensity. Observing the distribution of the unevenness can be further interpreted as an image. Therefore, the concept of biological resonance has long been applied to daily life, but most people do not realize it. In the concept of health care, “moderate exercise” has been advocated to ensure youth and health, but the so-called exercise is generally limited to muscle activity, promoting circulation and metabolization. Through regulating frequency, resonant waves can be used to promote the “exercise” at the cellular and even molecular level. It has a high potential not only for anti-aging and elimination of free radicals, but also systematic physiology regulation of the whole body, achieving complementary medical treatment. So we also call this technology “biomedical electronic medicine.”

R&D Pipeline

How we work

Pain Treatment

TRWR continues to conduct market driven clinical validations for differential treatment efficacies in different pain related diseases. We hope to increase the market competitiveness of our pain bioelectronic medicine.

Type 2 Diabetes Treatment

TRWR has validated the safety and efficacy of its type 2 diabetes bioelectronic medicine in facilitating better blood glucose control. Research continues in new dosages and other therapeutic applications including diabetes complications.

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1 The modulative effects of microcurrent electrical nerve stimulation on diabetic mice

2. An integrated systematic approach for investigating microcurrent electrical nerve stimulation (MENS) efficacy in STZ-induced diabetes mellitus

3. Transcutaneous Electrical Nerve Stimulator to Improve Blood Glucose Control in Patients With Type 2 Diabetes Mellitus

Type 1 Diabetes Treatment

TRWR’s type 1 diabetes bioelectronic medicine has been proven to delay disease onset from animal studies. TRWR continues to do research and development for type 1 diabetes treatments, ranging from delayed disease onset to better blood glucose control.

Sleep Disorder Treatment

TRWR continues to conduct clinical studies of its sleep disorder bioelectronic medicine in treating different causes of sleep disorder, such as insomnia and sleep apnea, etc. TRWR aims to provide a complete solution for sleep disorder treatment.

Diabetes Care

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Our Mission

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